Principal Scientist, Device Research & Development (RI)

Job Description
Semma Therapeutics, a biotechnology company focused on developing a stem cell-based cell therapy for Type 1 diabetes, is seeking a Principal Scientist to join its growing team. The full-time role will support design and development activities of Semma’s cell encapsulation device platforms. The Principal Scientist will be responsible for designing, writing, and executing study protocols, reports, and specifications specific to device and material design, process development, and advanced analytical development and evaluation. The successful candidate will have a balanced understanding of the device field, including mechanical and chemical design attributes that impact device engraftment and function. The position is located in Providence, RI and will report to the Associate Director of Device R&D.

Responsibilities:

  • Design and test new products and product improvements from concept through early phase prototyping
  • Collaborate with technicians and manufacturing engineers to ensure manufacturability of early concept-driven prototypes and assembly equipment
  • Identify, evaluate and manage vendors to support early phase prototyping
  • Generate material component libraries to support device innovation and discovery
  • Evaluate properties of new and existing materials in development (FTIR, DSC, SEM, TGA, XRD, EDS, PY-MS, etc.) to integrate into design feedback
  • Identify product failure modes and provide possible solutions through product modifications
  • Design preclinical studies to address critical device design aspects
  • Liaise with Semma’s manufacturing group to provide feedback on tech transfer
  • Work with the device design and simulation group to identify critical material parameters for effective design

Required qualifications:

  • M.S. with 8+ years of experience in Life Sciences, Bio-Engineering, Engineering, or related discipline
  • Over 3 years industry experience working with implantable biomedical devices
  • Demonstrated knowledge of polymer science, biomaterials, implantation systems, and medical devices
  • Working knowledge of FDA and other applicable medical device and combination product standards
  • Experience in chemical modification of biomaterials for medical devices
  • Ability to communicate effectively with a diverse range of scientists, physicians, engineers, regulatory specialists and business professionals
  • Demonstrated excellence in planning, executing, and analyzing experiments
  • Ability to quantify experimental results and present to groups effectively
  • Flexibility in working schedule to accommodate weekend work
  • Authorized to legally work in US

Preferred qualifications:

  • Deep understanding of the chemical properties of polymeric materials
  • Familiarity with polymer synthesis and molding technologies
  • Experience in combination products, preferably delivering living cells
  • Experience operating under design control
  • Ability to manage projects and forecast development activities through timelines to meet corporate goals

Please note that applicants should have authorization to work in the United States. Semma offers competitive pay, health insurance, time-off among other benefits. Please, fill out the form below and include your resume.

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